UC CEIN ICP-MS Core

UC CEIN Inductively Coupled Plasma Mass Spectrometry Analysis Core

The ICP-MS (Inductively Coupled Plasma Mass Spectrometry) Analysis Core houses the most advanced instrumentation for high-quality research and a range of analytical needs. ICP-MS analysis is available for researchers to rapidly determine the qualitative and quantitative composition with wide element coverage (~80 elements) in a single run. The uniquely constructed facility enables the chemical analysis at a part per trillion (ppt, pg/mL) scale with high sensitivity, which shows a much lower detection limit as compared to other analytical instruments (e.g., ICP-OES, AAS).

The ICP-MS Analysis Core Facility provides researchers with consultation about a variety of samples for effective decision-making based on the customer’s demands and interests. Furthermore, we offer services from sample preparation, such as developing acid digestion protocols, to data acquisition with optimizing experimental conditions. Well-trained staff will conduct the entire analysis including providing data reports with background correction.

Applications

    • Drug delivery (drug release kinetics, biodistribution)
    • Concentration measurement of metal-containing proteins
    • Impurities / composition / stoichiometric ratio / ion release kinetics
    • Toxic elements analysis (As, Pb, Cd, Hg, etc.) in food, soil
    • Trace metal analysis in drinking water and wastewater

        Technical Capabilities

          • Wide element coverage (~80 elements)
          • Low detection limits with high sensitivity (pg/mL)
          • Rapid multi-element quantitative analysis
          • Quick analysis for unknown sample
          • Available combination with HPLC

              Instrumentation

              ICP-MS:                      NexION 2000, PerkinElmer
              ICP-OES:                    ICPE-9000, Shimadzu
              Microwave digestion:  Titan MPS, PerkinElmer
              HotBlock:                    SC100, Environmental Express

              Contact

              Chong Hyun (Paul) Chang
              Technical Director of ICP-MS Core Facility
              chonghyun@ucla.edu
              CNSI Building #6511