The ICP-MS (Inductively Coupled Plasma Mass Spectrometry) Analysis Core houses the most advanced instrumentation for high-quality research and a range of analytical needs. ICP-MS analysis is available for researchers to rapidly determine the qualitative and quantitative composition with wide element coverage (~80 elements) in a single run. The uniquely constructed facility enables the chemical analysis at a part per trillion (ppt, pg/mL) scale with high sensitivity, which shows a much lower detection limit as compared to other analytical instruments (e.g., ICP-OES, AAS).
The ICP-MS Analysis Core Facility provides researchers with consultation about a variety of samples for effective decision-making based on the customer’s demands and interests. Furthermore, we offer services from sample preparation, such as developing acid digestion protocols, to data acquisition with optimizing experimental conditions. Well-trained staff will conduct the entire analysis including providing data reports with background correction.
Applications
- Drug delivery (drug release kinetics, biodistribution)
- Concentration measurement of metal-containing proteins
- Impurities / composition / stoichiometric ratio / ion release kinetics
- Toxic elements analysis (As, Pb, Cd, Hg, etc.) in food, soil
- Trace metal analysis in drinking water and wastewater
Technical Capabilities
- Wide element coverage (~80 elements)
- Low detection limits with high sensitivity (pg/mL)
- Rapid multi-element quantitative analysis
- Quick analysis for unknown sample
- Available combination with HPLC
Instrumentation
ICP-MS: NexION 2000, PerkinElmer
ICP-OES: ICPE-9000, Shimadzu
Microwave digestion: Titan MPS, PerkinElmer
HotBlock: SC100, Environmental Express
Contact
Chong Hyun (Paul) Chang
Technical Director of ICP-MS Core Facility
chonghyun@ucla.edu
CNSI Building #6511
