Frontiers and Careers in cryoEM Symposium

California NanoSystems Institute at UCLA, Los Angeles, CA

Symposium Agenda: Friday, April 27th

10:30 am – 11:00 am Registration and Breakfast
11:00 am – 11:10 am Welcome Remarks
Session I: Keynote and microED
Session Chair: Hong Zhou, UCLA
11:10 am – 11:50 am David Eisenberg, UCLA
“How CryoEM is helping to understand the molecular basis of neurodegeneration”
11:55 am – 12:25 pm Tamir Gonen, UCLA
“MicroED opens a new era for biological structure determination”
12:30 pm – 1:00 pm Jose Rodriguez, UCLA
“Atomic Resolution Electron Diffraction of Amyloid Nano-Structures”
1:00 pm – 2:00 pm Lunch and EICN Facility Tours
Session II: Membrane proteins and careers in cryoEM
Session Chair: Johan Hattne, UCLA
2:00 pm – 2:30 pm Jiangping Wu, Princeton University 
“How is electrical signal generated? Structural and mechanistic”
2:35 pm – 3:05 pm David Veesler, University of Washington
“Structural studies of coronavirus fusion proteins”
3:10 pm – 3:40 pm Maofu Liao, Harvard Medical School 
“Single-Particle Cryo-EM Studies of lipopolysaccharide transport”
3:40 pm – 4:00 pm Break
4:00 pm – 4:30 pm Rebecca Voorhees, Caltech
“Mechanism of protein targeting to the endoplasmic reticulum”
4:35 pm – 5:05 pm Jiansen Jiang, NIH/NHLBI
“CryoEM study of anion exchanger 1 reveals multiple conformations”
5:10 pm – 5:40 pm Rui Zhao, University of Colorado Anschutz Medical Campus 
“Structure and function of the spliceosome”
5:45 pm – 6:30 pm Poster Session and Reception

Symposium Agenda: Saturday, April 28th

8:30 am – 9:00 am Breakfast
9:00 am – 9:10 am Morning Introduction
Session III: New directions and methods
Session Chair: Peng Ge, UCLA
9:10 am – 9:40 am Hong Zhou, UCLA
“In situ structures of viral genome-protein complexes in action”
9:45 – 10:15 am Gabriel Lander, Scripps Research Institute
“No Phase Plate? No Problem! Smaller and Smaller using conventional TEM approaches”
10:20 am – 10:50 am Alexis Rohou, Genentech
“Supporting drug discovery with cryo-EM and image processing”
10:55 am – 11:10 am Break
11:10 am – 11:40 am Ali Punjani, University of Toronto
“New methods and developments in cryoSPARC”
11:45 am – 12:15 pm Jeff Lengyel, Thermo Fisher Scientific 
“In Situ structural biology – Advances in Cryo-Electron Microscopy”
12:20 pm – 1:30 pm Lunch and EICN Facility Tours
Session IV: Frontiers in cryoET
Session Chair: Marcus Gallagher-Jones, UCLA
1:30 pm – 2:00 pm Jun Liu, Yale School of Medicine
“High-throughput cryo-electron tomography: Visualizing transient channel during viral infection”
2:05 pm – 2:35 pm Dorit Hanein, Sanford-Burnham Prebys Medical Discovery Institute
“Unraveling the molecular details of mammalian cell nanoarchitecture: tying cryo-light
microscopy and cellular tomography”
2:40 pm – 3:10 pm Debnath Ghosal, Caltech
“In Situ Structures of the Bacterial Type IVB Secretion System by Electron Cryotomography”
3:15 pm – 3:30 pm Closing Remarks