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2nd Annual UC-Wide Drug Discovery Symposium

October 4-5, 2018, UCLA California NanoSystems Institute

Symposium Agenda: Thursday, October 4, 2018

9:00 am  – 10:00 am Breakfast & Registration
10:00 am – 10:10 am Welcome & Introductory Remarks  Jeff F. Miller (UCLA) & Robert Damoiseaux (UCLA)
10:10 am – 10:30 am UC-DDC: Overview Joe Wagner (UC DDC)An Overview of the UC Drug Discovery Consortium
10:30 am – 11:15 am UC Keynote Kevan Shokat (UCSF)Chemical Tricks for Drugging the Undruggable:  Discovery and development of the first K-Ras inhibitor
11:15 am – 12:00 pm UC Keynote Douglas Black (UCLA): Screening for Modulators of Alternative Pre-mRNA Splicing
12:00 pm – 1:00 pm Lunch & Posters
1:00 pm – 1:30 pm UC Keynote John MacMillan (UCSC): Natural Product-based Drug Discovery
1:30 pm – 2:15 pm UC Keynote Daniele Piomelli (UCI): Targeting lipid signaling pathways for drug discovery
2:15 pm – 3:00 pm UC Keynote Elizabeth Winzeler (UCSD): Phenotypic screening and cheminformatics in the search for next generation medicines for malaria
3:00 pm – 3:15 pm Coffee Break
3:15 pm – 3:40 pm DDC Seed Grant Recipient Gino Cortopassi (UCD)3D Scaffold hopping to identify novel Shc inhibitors
3:40 pm – 4:05 pm DDC Seed Grant Recipient Peter Bowers (UCLA)Development of Pleiotrophin Monoclonal Antibodies Targeting Leukemic Stem Cell Growth
4:05 pm – 4:30 pm DDC Seed Grant Recipient Alessandra Franco (UCSD)Immune modulatory peptides derived from the heavy constant region of immunoglobulins that activate human natural regulatory T cells
4:30 pm – 6:15 pm Oral Presentations, Posters & Reception

Symposium Agenda: Friday, October 5, 2018

8:00 am – 9:00 am Breakfast & Registration
9:00 am – 10:00 am UC-DDC Executive Committee Funding Opportunities; Mechanisms for Centrally Leveraging UC-Wide Assets; UC-Wide Institutional Knowledge for Acceleration of Drug Discovery
10:00 am – 10:30 am UC Keynote Bruce Hammock (UC Davis)Soluble epoxide hydrolase inhibitors to the clinic with blueprint and on to treating Parkinson’s and other cns disorders
10:30 am – 11:00 am UC Keynote Daniela Kaufer (UCB)Vascular dysfunction as a common driver of neuropathology in the aged and injured brain: A tale of translational study
11:00 am – 11:30 pm UC Keynote Maurizio Pellecchia (UCR)The UCR Center for Molecular and Translational Medicine: Challenges, Opportunities, and Success Stories
11:30 am – 11:45 am UC-DDC Education Programs Haim Weizman (UC-DDC Lead for Education): UC-DDC Education Programs Overview
12:00 pm – 1:00 pm Lunch & Posters
1:00 pm – 1:15 pm Trends in California Drug Discovery and Development Simone Fishburn (BioCentury and BioCentury Innovations)
1:15 pm – 1:30 pm Trends in California Drug Discovery and Development Maria Millan (California Institute for Regenerative Medicine)
1:30 pm – 1:45 pm Trends in California Drug Discovery and Development Mary Faris (Pfizer): Leveraging Internal Expertise and External Innovation towards Drug Discovery
 1:45 pm Closing Remarks & Wrap-Up