2021 Funded Projects

Ten unique and highly promising projects — including researchers in materials science, engineering, information technology, environmental sustainability, and life and biomedical sciences — were selected from an initial round of 79 letters of intent in a competitive process, with half of the funded teams led or co-led by women. Notably, four of the projects receiving grants relate to sustainability and clean energy technologies — a topic aligned with UCLA’s Sustainable LA Grand Challenge.

Big data and artificial intelligence

2D-Material-Based Optoelectronics for Optical Neural Networks and AI-Based Cameras

Investigators: Xiangfeng Duan; Aydogan Ozcan
A team headed by Xiangfeng Duan, a professor of chemistry and biochemistry and a CNSI member, is advancing photonics — energy-efficient technologies that use particles of light in place of the electrons used in electronics — for applications such as artificial intelligence and image capture. The team will explore ways to improve signal processing using two-dimensional materials, which are arranged in layers only a few atoms thick and derive special qualities from quantum mechanics.
Xiangfeng Duan

Xiangfeng Duan

Professor, UCLA Department of Chemistry & Biochemistry

Aydogan Ozcan

Aydogan Ozcan

Professor, UCLA Samueli School of Engineering

Nanomedicine

Shedding Light on the Protein Interactome

Investigators: Keriann Backus; Jahan Dawlaty; Steven Bensigner; Peter Tontonoz
A collaboration led by CNSI member Keriann Backus, assistant professor of biological chemistry and of chemistry and biochemistry, aims to develop a new method for mapping the protein interactions that are fundamental to almost every process in living things. The ability to label proteins with iodine using laser-mediated excitation could accelerate our understanding of the millions of interactions that are regulated by proteins in human cells, including interactions with drug molecules.
Keriann Backus

Keriann Backus

Associate Professor, UCLA Department of Chemistry & Biochemistry

Jahan Dawlaty

Jahan Dawlaty

Professor, USC Department of Chemistry

Steven Bensinger

Steven Bensinger

Chair, USC Department of Immunology and Immune Therapeutics

Peter Tontonoz

Peter Tontonoz

Professor, UCLA Pathology & Laboratory Medicine

Abuse Deterrent Opioid Prodrugs with Lowered Addiction Potential

Investigators: Cathy Cahill; Chris Evans; Heather Maynard
A collaboration led by CNSI member Keriann Backus, assistant professor of biological chemistry and of chemistry and biochemistry, aims to develop a new method for mapping the protein interactions that are fundamental to almost every process in living things. The ability to label proteins with iodine using laser-mediated excitation could accelerate our understanding of the millions of interactions that are regulated by proteins in human cells, including interactions with drug molecules.
Cathy Cahill

Cathy Cahill

Professor, UCLA Psychiatry & Biobehavioral Sciences

Heather Maynard

Heather Maynard

Professor, UCLA Department of Chemistry & Biochemistry

Chris Evans

Chris Evans

Professor-in-Residence, UCLA Department of Physiology

Improve Mitochondrial DNA Quality Control to Ward Off Aging and Mitochondrial Diseases

Investigators: Ming Guo, Bruce Hay, Robert Damoiseaux, Jonathan Wanagat
A collaboration led by CNSI member Keriann Backus, assistant professor of biological chemistry and of chemistry and biochemistry, aims to develop a new method for mapping the protein interactions that are fundamental to almost every process in living things. The ability to label proteins with iodine using laser-mediated excitation could accelerate our understanding of the millions of interactions that are regulated by proteins in human cells, including interactions with drug molecules.
Robert Damoiseaux

Robert Damoiseaux

Professor, UCLA Department of Molecular & Medical Pharmacology

Ming Guo

Ming Guo

Professor, UCLA Department of Neurology

Bruce A. Hay

Bruce A. Hay

Professor, Caltech Department of Biology

Jonathan Wanagat

Jonathan Wanagat

Clinical Professor, UCLA Department of Medicine

Synthetic Biology Approaches to Cannabinoid Diversification and Production

Investigators: Yi Tang; Neil Garg
A project dedicated to using yeast to produce potential medicinal compounds naturally found in the cannabis plant is helmed by CNSI member Yi Tang, professor of chemical and biomolecular engineering, of chemistry and biochemistry and of bioengineering, and Neil Garg, the Kenneth N. Trueblood Endowed Professor of Chemistry and Biochemistry and chair and distinguished professor of chemistry and biochemistry. This is the first UCLA-based grant to utilize the CNSI’s new Living Biofoundry, established through the National Science Foundation–funded BioPACIFIC Materials Innovation Platform.
Yi Tang

Yi Tang

Distinguished Professor, UCLA Chemical and Biomolecular Engineering

Neil Garg

Neil Garg

Distinguished Professor, UCLA Department of Chemistry & Biochemistry

Therapeutic Liver Targeting Nanoparticles for Peanut Allergy and Anaphylaxis

Investigators: Tian Xia; Andre Nel
A team led by Tian Xia, an associate adjunct professor of nanomedicine and CNSI member, is advancing a potential treatment for severe food allergies. The investigators have generated a nanoparticle meant to deliver an allergen directly to cells in the liver that regulate immune responses, potentially causing the body to tolerate that allergen.
Tian Xia

Tian Xia

Professor, UCLA Division of Nanomedicine at the Department of Medicine

Andre Nel

Andre Nel

Distinguished Professor, UCLA Medicine; Director of Research, California NanoSystems Institute at UCLA

Sustainability and clean energy technologies

The Future is Brown: Genetic Engineering Technology Innovation in Kelp

Investigators: Siobhan Braybrook; Tim Malloy

CNSI member Siobhan Braybrook, assistant professor of molecular, cellular and developmental biology, and Timothy Malloy, the Frank G. Wells Professor of Environmental Law, lead a project focused on genetically engineering kelp and other forms of brown algae to absorb more carbon dioxide from the atmosphere, as well as mapping the legal and regulatory issues related to such a technology.
Siobhan Braybrook

Siobhan Braybrook

Associate Professor, UCLA Department of Molecular, Cell and Developmental Biology

Tim Malloy

Tim Malloy

Professor, UCLA School of Law; Frank G. Wells Endowed Chair in Environmental Law

Laser-scribed Vanadium Oxide Cathodes for Grid-Scale Energy Storage

Investigators: Richard Kaner; Yuzhang Li

A team led by CNSI member Richard Kaner, the Dr. Myung Ki Hong Endowed Professor of Materials Innovation and distinguished professor of chemistry and biochemistry and of materials science and engineering, is furthering an approach for energy storage based on abundant, nontoxic zinc rather than lithium. The team’s goal is to create technology for grid-level batteries that store energy from sustainable but intermittent sources such as the sun and wind.
Richard Kaner

Richard Kaner

Distinguished Professor, UCLA Department of Chemistry & Biochemistry

Yuzhang Li

Yuzhang Li

Associate Professor, UCLA Sameuli School of Engineering

Precision Cultured Meat using Edible and Scalable Scaffolds

Investigators: Amy Rowat

CNSI member Amy Rowat, associate professor and vice chair of integrative biology and physiology, leads a team advancing a process for creating customized, labmade meat. By growing tissue on an edible scaffold, the researchers intend to produce food that can mimic the taste and texture of different cuts of steak without the environmental detriments that come with traditional livestock farming and processing.
Amy Rowat

Amy Rowat

Professor, UCLA Department of Integrative Biology & Physiology

Concentrated Solar-Thermal Co-Production of Hydroden and High-Value Solid Carbon Forms

Investigators: Tim Fisher; Yves Rubin; Mitchell Spearrin

A project developing a zero–carbon footprint process for generating hydrogen for energy is led by Tim Fisher, the John P. and Claudia H. Schauerman Endowed Professor of Engineering and chair and professor of mechanical and aerospace engineering, and Yves Rubin, professor of chemistry and biochemistry, both of whom are members of the CNSI. The team’s strategy would use sunlight to cleanly turn methane into hydrogen and graphite, a raw material for batteries.
Yves Rubin

Yves Rubin

Professor, UCLA Department of Chemistry & Biochemistry

Tim Fisher

Tim Fisher

Professor, UCLA Samueli School of Engineering, Department of Aerospace Engineering

Mitchell Spearrin

Mitchell Spearrin

Professor, UCLA Samueli School of Engineering, Department of Mechanical and Aerospace Engineering